Also, this won’t affect my enjoyment because most of my work will be midi rather than audio. This weekend I will give debugging this my best shot. I have other interfaces I can try to see if it’s the interface or a setting on my computer. So again, it’s pointing to TotalMix on my laptop. My guitar playing partner plugged his Axe I/O into his Mac mini and it was instant sound and easy routing. In the mean time, if you have any other suggestions, or if there is a TotalMix FX power user that has the app mastered around, I’d love to get their take on this situation. Thanks for all your patience and willingness to help. This weekend I’ll have a block of time to dig into the manuals and maybe some tutorials to see if I’ve missed something there. The thing is audio does work in total mix. Also, there has been a known issue with the security updates in Mac OS 10.14 Mojave, where a permission to access microphone (could never understand this one) must be set before audio will work in total mix. I know how to do that in Logic but can’t find a way of making sure of this in GP.

I looked at possible sources of the problem in Amplitube’s manual and came across their advice to make sure software monitoring is selected.

I’m tempted to go back to basics and make sure I have the correct driver and firmware installed and do some reading in the manuals.

Amplitube 5 full mac